The website CLLFAQ has a comprehensive list of questions and answers, acronyms, and gloassary for chronic lymphocytic leukemia.

Following is a linked index to the questions, organized by category.

General Information

What is chronic lymphocytic leukemia (CLL)? 
Can CLL be cured? 
Are there other types of leukemia? 
Are there subcategories of CLL? 
How common is CLL? 
What causes CLL?
Is CLL hereditary? 
What are the stages of CLL? 
What are constitutional symptoms? 
What is the survival outlook for people with CLL? 
What is “smoldering” CLL? 

Diagnosis, Diagnostic Procedures, & Other Tests

How is CLL diagnosed?
Should I seek a second opinion?
What are the blood count basics in CLL?
What do laboratory references ranges mean?
What is the difference between percentage of lymphocytes and absolute lymphocyte count (ALC)?
When do neutrophil counts become a problem?
When do platelet counts become a problem?
What are smudge cells?
What are immunoglobulins?
What questions should I ask in early visits with my hematologist?
What is flow cytometry?
What is polymerase chain reaction (PCR)?
What is the significance of IgVH gene mutational status in CLL?
What is the significance of CD38 in CLL?
What is the significance of ZAP-70 in CLL?
What is the significance of bcl-2 in CLL?
Will I need a bone marrow biopsy and how is it performed?
What information is detected in a bone marrow biopsy and aspirate?
What is the significance of beta-2-microglobulin in CLL?
What is fluorescence in situ hybridization (FISH)? 
What does trisomy mean?
What are some of the main prognostic indicators in CLL? 
What is tissue typing?
What is DiSC assay?

Blood Basics

If all this talk about blood isn’t too much and you’d like another good source for information, then click on over to Blood Basics  on the CLL Topics website for further discussion and clarification of these topics.


Should I start treatment as soon as possible?
What are the criteria for starting treatment?
How is CLL treated?
What drugs are used in treating CLLWhat questions should I ask prior to chemotherapy?
What side effects should I expect from chemotherapy?

Monoclonal Antibodies

Monoclonal antibody drugs for cancer treatment: How they workon the Mayo Clinic website, is a good introductionto them; and you’ll find much more when you Search for them under CLL Topics Updates  on the right sidebar.

What is tumor lysis syndrome?
Where in the CLL treatment plan does transplantation fit?
Should early stage patients have stem cells harvested and stored for future autologous transplant?
What is a mini-transplant?
What is a peripheral blood stem cell transplant (PBSCT)?
What is a cord blood transplant?
What is leukapheresis?
What about alternative/complementary therapies?
Is additional vitamin C recommended for people with CLL? 
What is a neutropenic diet?
What medical centers specialize in treating CLL?
What are clinical trials?
What constitutes a remission in CLL?
What is minimal residual disease (MRD)? 
What constitutes a relapse in CLL?

Search CLL Topics Updates

You might also do a search for some of the terms in these FAQs, using the Search link under CLL Topics Updates  in this website’s sidebar.

Related Disorders

What is monoclonal B-cell lymphocytosis (MBL)? 
Does CLL lead to other forms of cancer? 
What is the difference between CLL and lymphoma? 
What is small lymphocytic lymphoma (SLL)? 
What is hairy cell leukemia (HCL)? 
What is prolymphocytic leukemia (PLL)?
What is Richter’s syndrome? 
What is mantle cell lymphoma (MCL), and is it related to CLL? 
Is there a connection between shingles and CLL? 
What is autoimmune hemolytic anemia (AIHA)? 
What is idiopathic thrombocytopenic purpura (ITP)? 
What causes night sweats in CLL?

Other Questions

Should people with CLL wear some form of medical identification?
How will CLL affect my normal activities?
What is performance status?
Should people with CLL stop donating blood?
Are blood transfusions safe for people with CLL?
What are some of the terminal aspects of CLL?
What should I tell children?
What should I tell colleagues?
How may I be in touch with other CLL patients?
What are some of the leukemia-related organizations?
What are some of the dental considerations in CLL?


If you haven’t already, check out CarePages (on the Help drop-down menu), a free online support resource for patients and caregivers, friends and family.


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