Advanced Immunoglobulin Topics

eMedicine’s Medscape Reference offers comprehensive presentation of immuoglobulin topics including background, presentation, diagnosis, treatment, medications, follow-up, and complications. 

Immunoglobulin G Deficiency

E.g., Presentation:  “[T]he most frequent clinical problems in any type of IgG deficiency are repeated episodes of otitis and recurrent or chronic infections of the upper and lower respiratory tracts.” More…

Immunoglobulin A Deficiency

E.g., Presentation: “Previous studies based on analysis of blood donor banks have suggested that up to 90% of patients with selective immunoglobulin A deficiency (SIgAD) are asymptomatic. However, recent follow-up studies demonstrate that 80% of individuals with IgAD developed symptoms later in their life. More…

Immunoglobulin D Deficiency

E.g., Presentation: “No specific signs or symptoms are associated with isolated IgD deficiency; therefore, this condition is usually discovered incidentally during immunological laboratory testing (eg, quantitative serum immunoglobulin levels).”

Immunoglobulin M Deficiency

E.g., Presentation: “Patients may be asymptomatic, with a decreased IgM level noted during the investigation of other diseases, such as malignancies or autoimmune diseases.” More…


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